Flights from Saint Louis to Chicago from $110

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Airfare Deals Saint Louis to Chicago

On HolidayPrice.com you will find 5 direct and 1 connecting flights from Saint Louis to Chicago at a price of from $110. You can compare airfare deals from airlines and multiple travel sites, book and save on cheap plane tickets and last minute offers. Also check out STL - CHI flight schedule to find best flight time, convenient departure and arrival airports.

Sun

The cost of airline tickets from Saint Louis to Chicago (United States) and back without transfers can be found with the help of the calendar. Specify the search parameters: one way or round-trip, payment currency, click on the month/day you need and we will search for flights to Chicago.

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Cheap flights from Saint Louis
Cheap flights to Chicago
Airline tickets to United States

One way flight from Saint Louis to Chicago

Below are the prices of tickets for direct one-way flights from Saint Louis to Chicago. The cheapest flight from Saint Louis to Chicago starts from $110 – the departure date for this flight is 03 July 2025.

Sort by: Departure date Cheap flights Fast flights Direct flights

03.07.2025 Thursday

from $110 Farera

Economy Found today

1 Stopover 7 hours 12 min

Find Flights

02.07.2025 Wednesday

from $135 Trip.com

Economy Found today

1 Stopover 18 hours 37 min

Find Flights

*Prices include: baggage, hand luggage, airline fees and charges.

Round trip from Saint Louis to Chicago

You can buy a round-trip ticket from Saint Louis to Chicago (United States) and back using the table below. The best offer starts from $228, the flight dates are: there on 28 June 2025 year and back on 05 July 2025 year.

*Prices include: baggage, hand luggage, airline fees and charges.

Not found promotions and sales.

Flight Schedule Saint Louis to Chicago 2025

The current flight schedule for the route from Saint Louis to Chicago for today, tomorrow and the next few days. This schedule will help you decide on the time of departure and arrival, the airline, the flight number and the day of the week.

More than 7 flights every day, from 1hours 5min. Local departure and arrival times are indicated.

05:25 → 06:35

Southwest Airlines WN944

STL → MDW

Mo Tu We Th Fr - -

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05:40 → 06:45

Southwest Airlines WN944

STL → MDW

- - - - - Sa -

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06:00 → 07:21

American Airlines AA439

STL → ORD

Mo Tu We Th Fr Sa Su

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06:40 → 07:50

Southwest Airlines WN3803

STL → MDW

- Tu We - - - -

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06:50 → 08:00

Southwest Airlines WN3803

STL → MDW

- - We - - - -

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07:05 → 08:10

Southwest Airlines WN478

STL → MDW

Mo - - Th Fr - -

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07:20 → 08:43

American Airlines AA2324

STL → ORD

Mo Tu We Th Fr Sa Su

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07:25 → 08:35

Southwest Airlines WN3493

STL → MDW

- - - - - - Su

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08:05 → 09:30

United Airlines UA1334

STL → ORD

- - - - - Sa -

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08:10 → 09:35

United Airlines UA1334

STL → ORD

Mo Tu We Th Fr - Su

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11:00 → 12:05

Southwest Airlines WN3163

STL → MDW

Mo - - Th Fr - -

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11:45 → 12:50

Southwest Airlines WN3900

STL → MDW

- Tu We - - - -

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Show all

*Schedule is indicated only for direct scheduled flights and low-cost airlines.

Flight Information

Flying to Chicago from Saint Louis takes 01:04 minutes (excluding transfers). The distance between Saint Louis and Chicago is 262 miles (422 kilometers). Planes depart from Saint Louis between 00:00 and 23:55. The fastest flight from the company American Airlines with flight number AA 751. Flies for just 00:59 minutes with departure from Spirit of St. Louis Airport and arrival in O'Hare.

Airlines

Direct flight

There are 5 airlines that fly directly from Saint Louis to Chicago. The most popular company carrying out non-stop flights is American Airlines.

American Airlines: AA 5127, AA 1003, AA 2209
Southwest Airlines: WN 1702, WN 5082, WN 2614
United Airlines: UA 4499, UA 4633, UA 5713
Aer Lingus: EI 6395, EI 6389, EI 6390
Cape Air: 9K 1533

*Flight number

Flights with Transfers

Flights with transfers from Saint Louis to Chicago can be bought from 1 airlines:

Southwest Airlines: Las Vegas, Cleveland, Des Moines

*Transit cities

Airports

Airports serving the air communication between Saint Louis and Chicago. You can fly to Chicago from 1 Saint Louis airports. Planes arrive at 2 airport in Chicago.

Saint Louis airports:

Spirit of St. Louis Airport ~ 20 km* from $ 1 479

Chicago airports:

O'Hare ~ 25 km* from $ 58Chicago Midway ~ 14 km* from $ 83

*Distance from the airport to the city center

Aircraft

You can fly from Saint Louis to Chicago on board of 5 airlines that utilize 14 aircraft models.

Airbus A319
Airbus A320
Boeing 737
Boeing 737-700
Boeing 737-800

Boeing 737-900
Canadair reg jet 700
Canadair regional jet
Cessna Light Aircraft
Embraer 170

Embraer 175
Embraer EMB 175
Embraer ERJ-135/140/145 Regional Jet
Embraer RJ145

Connecting cities

The list of cities on transfer flights to Chicago from Saint Louis. The best options are to fly through: Las Vegas, Cleveland, Des Moines.

Las Vegas
Cleveland

Des Moines

Cheap airline tickets from Saint Louis to United States

Here is a list of flights from Saint Louis to United States purchased on HolidayPrice.com in the past 48 hours. If you find an interesting offer for cheap tickets, do not delay your purchase, prices change every 15 minutes.

Saint Louis - New York UA 4376 United Airlines Embraer ERJ-135/140/145 Regional Jet

17:00 Spirit of St. Louis Airport

in a way 2 hours 0 min Direct

19:00 Newark Liberty

Flights
from $74 05 September 2025

Saint Louis - Los Angeles WN 1841 Southwest Airlines Boeing 737-800

05:15 Spirit of St. Louis Airport

in a way 3 hours 50 min Direct

09:05 Los Angeles

Flights
from $136 18 July 2025

Saint Louis - Miami WN 3780 Southwest Airlines Boeing 737-700

13:15 Spirit of St. Louis Airport

in a way 2 hours 40 min Direct

15:55 Fort Lauderdale Executive Airport

Flights
from $77 13 September 2025

Saint Louis - Chicago AA 751 American Airlines Airbus A319

04:01 Spirit of St. Louis Airport

in a way 0 hours 59 min Direct

05:00 O'Hare

Flights
from $110 03 July 2025

Saint Louis - San Francisco WN 5713 Southwest Airlines Boeing 737-700

19:30 Spirit of St. Louis Airport

in a way 4 hours 5 min Direct

23:35 Norman Y. Mineta San Jose

Flights
Find 04 July 2025

All flights from Saint Louis

Flights from United States to Chicago

Here are the cheapest flight bookings from United States to Chicago made by users of our website. If you didn’t find your flight destination, use the search bar at the top of the page.

New York - Chicago UA 761 United Airlines Boeing 737-800

13:00 LaGuardia

in a way 2 hours 0 min Direct

15:00 O'Hare

Flights
from $45 08 July 2025

Los Angeles - Chicago UA 910 United Airlines Boeing 737-800

10:23 Los Angeles

in a way 3 hours 37 min Direct

14:00 O'Hare

Flights
from $46 12 July 2025

Miami - Chicago AA 2796 American Airlines Boeing 767-300

17:05 Miami

in a way 2 hours 55 min Direct

20:00 O'Hare

Flights
from $64 16 August 2025

Miami - Chicago WN 1626 Southwest Airlines Boeing 737

13:35 Fort Lauderdale Executive Airport

in a way 3 hours 0 min Direct

16:35 Chicago Midway

Flights
from $64 16 August 2025

San Francisco - Chicago UA 1800 United Airlines Airbus A319

04:15 San Francisco

in a way 3 hours 45 min Direct

08:00 O'Hare

Flights
from $69 20 October 2025

All flights to Chicago

Tips for buying a ticket

Saint Louis – Chicago – Saint Louis round-trip route are always cheaper than tickets purchased there and back separately.

Cheap flights from Saint Louis to Chicago — Chicago city

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